Objective : To explore the anatomical basis of vein of Marshall (VOM) chemical ablation for the
treatment of persistent atrial fibrillation. Methods : Thirty-four 10% formalin-fixed adult heart specimens were
selected and the VOM was dissected and statistically analyzed. Using a vernier caliper, the VOM length, the outer
diameter of its end, the distance from the VOM opening to the orifice of coronary sinus, and the outer diameter
of the coronary sinus and the outer diameter of the coronary sinus at the point where the VOM converges were
measured. The length of the coronary sinus and its longitudinal and transverse diameters, as well as the angle
between the VOM and the coronary sinus, were measured. Results : The VOM length was( 32.53±11.72) mm.
The outer diameter of the end of VOM was( 1.82±0.50) mm, and the proportion of cases that could be accessed
using a 5F JR4 guiding catheter was 60.71%. The distance from the VOM opening to the orifice of the coronary
sinus was( 36.21±11.57) mm. The outer diameter at the point where the VOM converges with the coronary sinus
was( 7.42±2.09) mm. The angle between the VOM and the coronary sinus was (43.98±15.75)°. The length of the
coronary sinus was( 61.84±15.37) mm, with a longitudinal diameter of the sinus orifice being( 12.61± 3.15) mm,
and a transverse diameter of( 8.07±2.25) mm. The differences between the longitudinal diameter and the transverse
diameter of the coronary sinus orifice, as well as the outer diameter at the point where the VOM converges with
the coronary sinus, were statistically significant. The differences between the lengths of the coronary sinus and
the distance from the VOM opening to the coronary sinus orifice were also statistically significant. The other items
showed no statistically significant differences in comparison between genders. Conclusion : This study measured
the length and outer diameter of VOM at a gross anatomical level,providing morphological references for the
application of VOM chemical ablation therapy in treating persistent atrial fib rillation.
Clinical anatomy of vein of Marshall chemical ablation for persistent atrial fibrillation[J]. Chinese Journal of Anatomy, 2024, 47(4): 299-302 https://doi.org/10.3969/j.issn.1001-1633.2024.04.004